MTHFR, Nutrigenomics and Epigenetics

Epigenetics, MTHFR and Nutrigenomics

Being told that you have an MTHFR gene mutation can be a scary thing. It is now well established that MTHFR mutations have potentially numerous negative health implications in epigenetics. The variant that is most problematic is the C677T variant. This variant produces a thermolabile (unstable in heat) enzyme with reduced activity (a much less efficient and effective enzyme.) The degree of enzyme thermolability is much more exaggerated when a person has two abnormal alleles as opposed to one abnormal allele.

Folic acid

Folic Acid – Why You Should Avoid it With an MTHFR Mutation

*Consult your doctor before making any changes in your dietary intake related to folic acid. This article is for informational purposes only and not a substitute for medical advice.

Nowadays, many people have issues such as fatigue, irritability, brain fog, anxiety, insomnia and other aches and pains without an apparent cause. Some might think that genetic disorders are the obvious cause.

What is MTHFR Gene Mutation

What is MTFHR Gene Mutation?

MTHFR Gene Mutation – Some families have a history of heart diseases or miscarriages. Others suffer from migraines or irritable bowel syndrome or depression. All these health conditions may share a common element: the presence of a faulty gene in your body known as methylenetetrahydrofolatereductase (MTFHR).

There are as many as 50 known variants of MTFHR,