These conditions are associated with MTHFR genetic mutation in research: Several can be considered a genetic disorder since treating the mutation will resolve the illness. There continues to be correlations of health problems with MTHFR that are not mentioned here.
You wake up and decide that you are sick and tired of chronically feeling lousy. You make an appointment with your doctor and blood tests are performed. They come back negative, and you go on your way feeling frustrated. You see another doctor, then another, and another. The answer is always the same: Nothing. You finally are referred to a psychologist as there is no medical answer and you walk away with a prescription for antidepressants or other mood altering medication.
Being told that you have an MTHFR gene mutation can be a scary thing. It is now well established that MTHFR mutations have potentially numerous negative health implications in epigenetics. The variant that is most problematic is the C677T variant. This variant produces a thermolabile (unstable in heat) enzyme with reduced activity (a much less efficient and effective enzyme.) The degree of enzyme thermolability is much more exaggerated when a person has two abnormal alleles as opposed to one abnormal allele.
Have you ever wondered why are we all so alike and yet so different? All human beings possess genes, but they vary for every person. This is the reason why one human being can remain fit and strong all through his life while other can fall ill frequently. One of the major reasons for this is the variation in a gene named MTHFR.
MTHFR Gene Mutation – Some families have a history of heart diseases or miscarriages. Others suffer from migraines or irritable bowel syndrome or depression. All these health conditions may share a common element: the presence of a faulty gene in your body known as methylenetetrahydrofolatereductase (MTFHR).
There are as many as 50 known variants of MTFHR,