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This product contains Methylfolate for MTHFR and supports methylation deficiency and methylation reactions, important for metabolism of homocysteine, by providing a combination of targeted nutrients and cofactors, such as trimethylglycine at 550 mg and MSM at 50 mg per serving.* This formula includes the antioxidant vitamins C and E, as well as high-potency riboflavin, vitamin B6, folate, and vitamin B12. In addition, this formula includes a biologically active form of folate (5-methyltetrahydrofolic acid or 5-MTHF), which is normally produced and available to the body only at the final stage of the folate metabolic process. This is a great product for those who want the best multivitamin for MTHFR mutation. When searching for MTHFR supplements always look for the best formula.
Storage instructions: Store at room temperature away from direct sunlight. Keep this bottle tightly closed.
Directions of methylfolate dosage according to your MTHFR mutations (adults and children over 12 years of age):
No mutations or MTHFR A1298C Heterozygous (1 mutation): Take 1 capsule once a day with a meal
MTHFR A1298C Homozygous (2 mutations) or MTHFR C677T Heterozygous (1 mutation): Take 2 capsules per day with meals
MTHFR C677T Homozygous (2 mutations) or Compound Heterozygous (1 mutation of C677T and 1 of A1298C): Take 3 capsules per day with meals
Or take as directed by your healthcare professional. For children under 12 years old consult their pediatrician.
Always increase the amount slowly. Start with 1 capsule per day, you may increase the dosage 1 capsule every 3 days according to your MTHFR mutations, not to exceed the daily recommended for your MTHFR mutations. Or take as directed by your healthcare professional. If you have any unwanted reaction stop immediately and consult your healthcare professional for advice.
Warning: Consult your healthcare professional before use if pregnant, nursing, taking medications, or for any use by minors. Do not use if safety seal is broken or missing. KEEP OUT OF REACH OF CHILDREN. This product is not intended to diagnose, treat, cure, or prevent any disease. For nutritional use only.
Serving size 2 vegetarian capsules
Servings per container 45
Amount Per Serving
Vitamin C (as ascorbic acid)
Vitamin E (as alpha-tocopherol acetate
(20 IU) 13 mg
|Riboflavin (as riboflavin 5′-phosphate)|
Vitamin B6 (as pyridoxal 5′-phosphate)
MethylFolate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
2500 mcg DFE
Vitamin B12 (as methylcobalamin)n)
Magnesium (as magnesium citrate)
Choline (as choline bitartrate)
Trimethylglycine (as betaine anhydrous
Beet (Beta vulgaris) (root)
*Daily Value (DV) not established.
Other ingredients: Vegetarian capsule (hypromellose), cellulose, silica.
Quatrefolic® is a registered trademark of Gnosis S.P.A. U.S. Patent No. 7,947,662
* This statement has not been evaluated by the Food Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.