MTHFR Gene Mutation – Some families have a history of heart diseases or miscarriages. Others suffer from migraines or irritable bowel syndrome or depression. All these health conditions may share a common element: the presence of a faulty gene in your body known as methylenetetrahydrofolatereductase (MTFHR).
There are as many as 50 known variants of MTFHR, of which the two major ones are C677T and A1298C. This gene encodes an enzyme by the same name.If mutated, this genebecomes a genetic variant, which causes it’s enzymes to work at a slower rate than they would normally work. This enzyme is responsible forbreaking down folic acid into its usable form of folate called 5-L-MethylTetrahydroFolate. This process is essential for methylation to occur in the entire human body. Methylation is a process of cellular repair, detoxification, neurotransmitter production,regulation of gene expression and is also responsible for a healthy immune system functioning.
The presence of MTFHR mutations can lead to serious problems in the body. One of the ways through which MTFHR may affect your immune system is by lowering your body’s ability to produce glutathione. This is the body’s primary antioxidant and detoxifier.A reduction of this vital nutrient in the body can lead to increased stress, lesser tolerance to toxic exposures and premature aging.
Considering that over 80% of the population has at least one mutation on one of the two most important alleles of this gene it is critical to find out if you also have a mutation. A genetic test is only needed once as your DNA will never change. You can order here a home test kit for MTHFR gene mutation. The two most important alleles are: C677T and A1298C.
The cheek swab kit is the most convenient and non invasive way to test for an MTHFR gene mutation. Results will be posted within one to two weeks.